Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type,Cyp1b1knockout, andCYP1B1humanized mice
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چکیده
منابع مشابه
Transplacental arsenic carcinogenesis in mice.
Our work has focused on the carcinogenic effects of in utero arsenic exposure in mice. Our data show that a short period of maternal exposure to inorganic arsenic in the drinking water is an effective, multi-tissue carcinogen in the adult offspring. These studies have been reproduced in three temporally separate studies using two different mouse strains. In these studies pregnant mice were trea...
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Mice. The same strains were used in our previous studies of the teratogenic effects of ENU, i. and C57L/J. They were mated at approximately 10 weeks of age. The females were observed daily for vaginal plugs and palpated to determine preg nancy. The day that vaginal plugs were found was recorded as Day 0. Treatment Schedule and Observation Procedure. ENU was freshly prepared as a 1% solution in ...
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ژورنال
عنوان ژورنال: Molecular Carcinogenesis
سال: 2016
ISSN: 0899-1987
DOI: 10.1002/mc.22480